Information on the invasive potential of a species is crucial to assess likely future impacts on biodiversity and to improve the scientific basis for decision-making on biological invasions. In this context, INVAXEN aims to study the invasive biology of Xenopus laevis, one of the world’s most widely distributed amphibians with invasive populations established worldwide. As such, INVAXEN will attempt to develop a robust predictive species distribution model that will allow predicting the potential future spread of this species. The RBINS workpackage in this project deals with the population genetics and phylogeography of the species, based on mtDNA sequence variation and high-throughput genomic analysis using Restriction-Site Associated DNA sequencing.